In Los Angeles, the police put a residential building in quarantine. Meanwhile, the flight attendants of Trans Sky Air, Jenny and Paula, are welcoming the passengers of flight TS Air 318 from Los Angeles to Kansas City with Captain Forrest and Co-Pilot Wilsy. Teacher Henry brings a cage of hamsters to the cabin, but Jenny tells him that it should be transported in the cargo hold. However, one hamster bites the fingertip of the fat passenger Ralph. Soon, Ralph vomits and becomes aggressive, attacking Paula. The male passengers help Jenny and lock Ralph in the bathroom while Captain Forrest requests an emergency landing. When they land in the airport, they find all the gates closed and the Captain heads the plane to an abandoned terminal. Employee Ed helps the crew and passengers to reach the exit, but they find that they are closed. Soon they discover that the place is in quarantine and there is no way out.

With a ticking bomb locked to his neck, a young freerunner races against the clock and all types of baddies to get from one end of the city to the other to save himself and his girlfriend.

The middle-class couple Linda Hanson and Jim Hanson lives a wasted and routine relationship with their two daughters in their comfortable house in the suburbs. On a Thursday morning, the local sheriff visits Linda and tells her that her husband died in a car accident on the previous day. On the next morning, when Linda awakes, she finds Jim safe and sound at home. When she awakes on the next morning, she realizes that her days are out of order, but her family and friends believe she is insane.